Cheeseburger pie is a delightful twist on the classic cheeseburger, bringing together all the flavors you love in a savory, easy-to-make dish. Made with Bisquick, this casserole is loaded with ground beef, cheese, and a sumptuous filling that comes together quickly for busy weeknight dinners or hearty weekend meals.

Why You’ll Love This Casserole
- Quick and Easy: This recipe comes together in under an hour, making it the perfect weekday dinner solution.
- Flavorful and Filling: With the combination of ground beef, cheese, and classic condiments, every bite bursts with mouthwatering flavor.
- Versatile: Customize it with your favorite toppings like pickles, tomatoes, or extra cheese!
- Kid-Friendly: This hearty dish appeals to all ages, making it a hit at the family dinner table.
Ingredients
- 1 lb ground beef
- 1/2 cup chopped onion
- 1/2 cup chopped green bell pepper (optional)
- 1 cup shredded cheddar cheese
- 1/4 cup ketchup
- 1/4 cup mustard
- 1/2 teaspoon salt
- 1/2 teaspoon black pepper
- 2 cups milk
- 1 1/2 cups Bisquick mix
- 3 large eggs
Directions
- Preheat the Oven: Preheat your oven to 400°F (200°C).
- Cook the Beef: In a large skillet over medium heat, cook the ground beef, chopped onion, and green bell pepper (if using) until the beef is browned and vegetables are tender. Drain any excess grease.
- Add Flavor: Remove the skillet from the heat. Stir in the ketchup, mustard, salt, and pepper until well mixed. Add half of the shredded cheddar cheese and mix until evenly distributed.
- Make the Batter: In a mixing bowl, whisk together the Bisquick mix, milk, and eggs until smooth.
- Combine: Pour the beef mixture into a greased 9×13 inch baking dish. Evenly spread the Bisquick batter over the top of the beef mixture.
- Bake: Place the dish in the preheated oven and bake for 25 minutes.
- Add Cheese: Carefully remove the casserole from the oven. Sprinkle the remaining cheddar cheese on top and return to the oven.
- Final Bake: Bake for an additional 10-15 minutes or until the cheese is melted and bubbly and a toothpick comes out clean when inserted in the center.
- Serve: Let it cool for a few minutes before slicing. Serve warm and enjoy!

Toppings and Variations
One of the best things about cheeseburger pie is how adaptable it is. Here are a few ideas to elevate your dish even further:
- Add Veggies: Mix in your favorite vegetables, such as diced tomatoes or corn, for extra flavor and nutrition.
- Top with Pickles: After baking, add sliced pickles on top for that authentic burger taste.
- Seasoning Variations: Experiment with spices like garlic powder, cayenne pepper, or smoked paprika for a different flavor profile.
- Swapping Meats: Ground turkey or chicken can be substituted for beef for a leaner option.
Serving Suggestions
Cheeseburger pie is hearty enough to stand alone, but here are some ideas for sides that pair wonderfully:
- Coleslaw: A crunchy, tangy side that complements the richness of the pie.
- French Fries or Sweet Potato Fries: Add some classic burger-side flair.
- Side Salad: A fresh garden salad with a light vinaigrette adds balance and freshness.
Storage Tips
This dish is great for meal prep! Here’s how to store any leftovers:
- Refrigerate: Place any leftover pie in an airtight container and refrigerate for up to 3 days. Reheat in the microwave or oven.
- Freeze: For longer storage, individually slice and wrap portions in plastic wrap, then place in a freezer-safe bag. It can be frozen for up to 2 months. Thaw in the refrigerator overnight before reheating.
Frequently Asked Questions
Can I make this recipe gluten-free?
Yes! Use a gluten-free Bisquick mix, and make sure to confirm that all other ingredients you are using are gluten-free.
Can this be made without meat?
Absolutely! Substitute the ground beef with black beans or lentils for a delicious vegetarian option.
How can I adjust the spiciness?
You can adjust the level of spiciness by adding hot sauce to the beef mixture or using pepper jack cheese instead of cheddar for a kick.
Conclusion
Cheeseburger pie with Bisquick is a straightforward and satisfying recipe that brings the joys of a cheeseburger into an easy-to-make casserole. Perfect for all families, it’s not only delicious but also allows for customizations that everyone will love. Whether it’s for a weeknight dinner or a gathering, this dish is sure to be a favorite.
Start cooking today and enjoy a slice of this delightful savory dish with your loved ones!

Cheeseburger Pie with Bisquick
Ingredients
Method
- Preheat your oven to 400°F (200°C).
- In a large skillet over medium heat, cook the ground beef, chopped onion, and green bell pepper (if using) until the beef is browned and vegetables are tender. Drain any excess grease.
- Remove the skillet from the heat. Stir in the ketchup, mustard, salt, and pepper until well mixed. Add half of the shredded cheddar cheese and mix until evenly distributed.
- In a mixing bowl, whisk together the Bisquick mix, milk, and eggs until smooth.
- Pour the beef mixture into a greased 9x13 inch baking dish. Evenly spread the Bisquick batter over the top of the beef mixture.
- Place the dish in the preheated oven and bake for 25 minutes.
- Carefully remove the casserole from the oven. Sprinkle the remaining cheddar cheese on top and return to the oven.
- Bake for an additional 10-15 minutes or until the cheese is melted and bubbly and a toothpick comes out clean when inserted in the center.
- Let it cool for a few minutes before slicing. Serve warm and enjoy!